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Search Results for " glycoprotein vi "

Targets

6

Compounds

3

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T11824LL Lanraplenib GS-9876 Syk
Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases. Lanraplenib inhibits SYK activity in platelets via the glycoprotein VI ...
T61697 GPVI antagonist 1
GPVI antagonist 1 (compound 5) functions as an antagonist for the glycoprotein VI (GPVI) platelet receptor. It effectively inhibits collagen-induced platelet aggregation, demonstrating an IC50 value of 25.3 μM [1].
T11824L Lanraplenib monosuccinate GS-9876 monosuccinate Syk
Lanraplenib monosuccinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans. Lanraplenib monosuccinate is a highly selective and orally...
T62250 GPVI antagonist 2
GPVI antagonist 2 (Compound 1) is a potential Glycoprotein VI (GPVI) antagonist, able to act on collagen (IC50: 0.35 μM), CRP (IC50: 0.80 μM), convulxin (IC50: 195.2 μM), thrombin (IC50. 81.38 μM). GPVI antagonist 2 is a...
T11824 Lanraplenib succinate GS-9876 succinate Syk
Lanraplenib succinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans. Lanraplenib succinate is a highly selective and orally active S...
T61811 GPVI antagonist 3
GPVI antagonist 3 (Compound 2) is a potential antagonist that shows promising antiplatelet activity by selectively inhibiting the interaction between the Glycoprotein VI (GPVI) receptor and its ligands. It demonstrates p...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-00605 GPVI Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Glycoprotein VI (GPVI) is a 63 kDa platelet/megakaryocyte-specific type I transmembrane glycoprotein of the immunoglobulin superfamily that is an important collagen receptor and initiator of platelet activation, aggregat...
TMPK-01190 GPVI Protein, Human, Recombinant (His) Human HEK293 Cells
Although platelets are best known for their role in hemostasis, they are also crucial in development, host defense, inflammation, and tissue repair. Many of these roles are regulated by the immune-like receptors glycopro...
TMPK-01302 GPVI Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
Although platelets are best known for their role in hemostasis, they are also crucial in development, host defense, inflammation, and tissue repair. Many of these roles are regulated by the immune-like receptors glycopro...
TargetMol